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师资队伍

硕士生导师

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炮制学科:裴科导师简介

发布日期:2025-09-22   作者:    点击:


裴科,女,1986年7月出生,毕业于南京中医药大学。博士,副教授,yl8cc永利官网硕士生导师,yl8cc永利官网副院长。先后主持科研项目10项,发表论文53篇,其中中文核心(或SCI)论文51篇,获批专利2项。

研究学科(领域):中药炮制学

研究方向:中药炮制物质基础及作用机制研究


科研项目:

1、基于活血化瘀类中药酒制的瓶颈突破和地产矿物药炮制机制的学科交叉研究(202304051001044),山西省科技厅青年科技创新团队,2023.08 - 2026-08,50万元,在研,主持。

2、以川芎酒炙为例探究不同黄酒类型对酒炙的影响(202203021211221),山西省科技厅自由探索面上项目,2023.01 – 2025.12,8万元, 在研, 主持

3、黄芪调控神经血管偶联在补阳还五汤改善慢性脑缺血中的作用确证与机制探索(U21A20410),国家自然科学基金委员会联合基金项目,2022.01 – 2025.12, 260万元,在研,参与。

4、以山茱萸酒制前后配伍黄芪治疗糖尿病肾病为例探究炮制和药对协同增效的物质基础及作用机制(82074022),国家自然科学基金委员会面上项目,2021.01- 2024.12,56万元,在研,参与。

5、基于成分与归经关联的“活性化学成分群模拟炮制”探究川芎酒制治疗脑血栓的科学内涵(81703704),201801-202012,21万元,结题,主持。


代表性成果:

1、Hui Zhu, Yating Zhang, Yu Duan, Ke Pei, Sicong Tu, Yijing Chen, Hao Cai*. Pharmacokinetic evaluation of Sinisan containing vinegar-processed products in depressive rats, a comprehensive perspective of ‘individual herb, herb-pair, and herbal formula. Journal of Ethnopharmacology, 2023, 317: 116817

2、Xin Liu, Hao Cai*, Minjie Niu, Hui Yu, Mengqing Wang, Hui Zhu, Gang Cao, Ke Pei, Yu Duan, Jiantao Song. An integrated strategy of secondary metabolomics and glycomics to investigate multi-component variations in wine-processing of medicinal herbs and functional foods: A case study on Fructus Corni. Arabian Journal of Chemistry, 2023, 16: 104525

3、Ke Pei, Lilong Cao, Gang Cao, Hao Cai*, Yan Ning*, Tingting Zhao, Lin Sun, Haixin Liu, Shuosheng Zhang. A reasonable evaluation of Chuanxiong Rhizoma processing with wine through comparative pharmacokinetic study of bioactive components: dominant effect on middle cerebral artery occlusion model rats. Journal of Analytical Methods in Chemistry, 2022:8252038

4、Yan Ning, Ke Pei*, Gang Cao, Hao Cai*, Xiao Liu, Lilong Cao, Shuosheng Zhang, Baochang Cai. Comparative study on pharmacokinetics of four active compounds in rat plasma after oral administration of raw and wine processed Chuanxiong Rhizoma. Molecules, 2020, 25(1): 93

5、Hao Cai*, Yangyang Xu, Li Xie, Yu Duan, Jia Zhou, Jing Liu, Minjie Niu, Yating Zhang, Lin Shen, Ke Pei, Gang Cao. Investigation on spectrum-effect correlation between constituents absorbed into blood and bioactivities of Baizhu Shaoyao San before and after processing on ulcerative colitis rats by UHPLC/Q-TOF-MS/MS coupled with gray correlation analysis. Molecules. 2019, 24(5): 940


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